Windmill Street appears on the John Roque map from the 1750s.
Windmill Street lead to the original Middlesex County Hospital.
It perpetuates the memory of an early windmill, perhaps the feudal mill of the Manor of Tottenham Court, which stood where Charlotte Street now meets Windmill Street. The street was originally part of a Tudor path across the fields to the mill, now traceable as Store Street, the passage through London University’s Senate House and Guilford Street. The mill was still standing in about 1745, when Nollekens the sculptor was taken there on country walks as a boy, and had to pay the miller a halfpenny for permission to cross his grounds.
